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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GOT1L1
All Species:
14.85
Human Site:
Y153
Identified Species:
27.22
UniProt:
Q8NHS2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8NHS2
NP_689626.2
421
47305
Y153
M
G
F
T
V
Y
E
Y
S
V
W
D
P
K
K
Chimpanzee
Pan troglodytes
A5A6K8
413
46215
Y159
G
F
K
D
I
R
S
Y
R
Y
W
D
A
E
K
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_532809
406
45869
Y153
M
G
F
T
V
C
E
Y
S
L
W
D
S
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q7TSV6
404
45439
Y153
M
G
F
I
V
Y
E
Y
S
I
W
N
A
S
D
Rat
Rattus norvegicus
P13221
413
46410
Y159
G
F
K
D
I
R
S
Y
R
Y
W
D
A
E
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507985
380
42638
H144
S
S
P
T
W
E
N
H
N
G
V
F
T
A
A
Chicken
Gallus gallus
P00504
412
45917
T157
A
G
F
K
D
I
R
T
Y
R
Y
W
D
A
A
Frog
Xenopus laevis
NP_001080543
411
46052
A156
A
G
F
K
D
I
R
A
Y
R
Y
W
D
A
A
Zebra Danio
Brachydanio rerio
NP_998222
410
45964
L168
P
V
K
R
G
L
D
L
A
G
F
L
G
D
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_725534
437
48561
S171
A
G
F
T
T
V
K
S
Y
R
Y
W
D
Q
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22067
408
45475
D150
A
G
F
T
T
V
A
D
Y
T
F
W
D
Y
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P46645
405
44248
F151
A
G
L
S
V
E
Y
F
R
Y
Y
D
P
A
T
Baker's Yeast
Sacchar. cerevisiae
P23542
418
46039
Y152
Q
G
L
K
T
A
T
Y
P
Y
W
A
N
E
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.9
N.A.
76.7
N.A.
71.5
39.4
N.A.
33.9
37.7
37.7
39.6
N.A.
35.7
N.A.
35.3
N.A.
Protein Similarity:
100
57.9
N.A.
85.5
N.A.
81.7
57.7
N.A.
51.7
58.1
56.5
58.6
N.A.
52.4
N.A.
54.3
N.A.
P-Site Identity:
100
26.6
N.A.
73.3
N.A.
60
26.6
N.A.
6.6
13.3
13.3
0
N.A.
20
N.A.
20
N.A.
P-Site Similarity:
100
40
N.A.
86.6
N.A.
73.3
40
N.A.
20
20
20
20
N.A.
40
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.8
27.5
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
51.5
46.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
39
0
0
0
0
8
8
8
8
0
0
8
24
31
24
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
16
16
0
8
8
0
0
0
39
31
8
16
% D
% Glu:
0
0
0
0
0
16
24
0
0
0
0
0
0
24
0
% E
% Phe:
0
16
54
0
0
0
0
8
0
0
16
8
0
0
0
% F
% Gly:
16
70
0
0
8
0
0
0
0
16
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
16
16
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
24
24
0
0
8
0
0
0
0
0
0
16
24
% K
% Leu:
0
0
16
0
0
8
0
8
0
8
0
8
0
0
0
% L
% Met:
24
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
0
0
0
8
0
8
0
0
8
8
0
8
% N
% Pro:
8
0
8
0
0
0
0
0
8
0
0
0
16
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% Q
% Arg:
0
0
0
8
0
16
16
0
24
24
0
0
0
0
0
% R
% Ser:
8
8
0
8
0
0
16
8
24
0
0
0
8
8
0
% S
% Thr:
0
0
0
39
24
0
8
8
0
8
0
0
8
0
16
% T
% Val:
0
8
0
0
31
16
0
0
0
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
47
31
0
0
0
% W
% Tyr:
0
0
0
0
0
16
8
47
31
31
31
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _